Corneal Infection Therapy with Topical Bacteriophage Administration
نویسندگان
چکیده
Staphylococcus aureus is a major pathogen in bacterial keratitis, a vision-threatening disease. Although the incidence of S. aureus keratitis varies worldwide, the increasing trend of resistance to certain antibiotics makes this condition an important, global, healthcare concern. We report the case of a 65-year-old woman with nosocomial left-eye corneal abscess and interstitial keratitis.The patient then undergo topical Phage therapy with successful results.
منابع مشابه
Evaluating the Efficacy of Topical and Subconjunctival Diclofenac in the Improvement of Corneal Alkali Burn in Rabbits
Objective- To compare the effects of topical eye-drop and subconjunctival administration of diclofenac on improvement of experimental corneal alkali wound in rabbits eyes. Design- Experimental study. Animal- fifteen rabbits. Procedures- Alkali wounds were inflicted on the central corneas of 15 rabbits which we...
متن کاملEarly addition of topical corticosteroids in the treatment of bacterial keratitis.
IMPORTANCE Scarring from bacterial keratitis remains a leading cause of visual loss. OBJECTIVE To determine whether topical corticosteroids are beneficial as an adjunctive therapy for bacterial keratitis if given early in the course of infection. DESIGN, SETTING, AND PARTICIPANTS The Steroids for Corneal Ulcers Trial (SCUT) was a randomized, double-masked, placebo-controlled trial that over...
متن کاملThe potential of desferrioxamine-gallium as an anti-Pseudomonas therapeutic agent.
The opportunistic pathogen Pseudomonas aeruginosa causes infections that are difficult to treat by antibiotic therapy. This bacterium can cause biofilm infections where it shows tolerance to antibiotics. Here we report the novel use of a metallo-complex, desferrioxamine-gallium (DFO-Ga) that targets P. aeruginosa iron metabolism. This complex kills free-living bacteria and blocks biofilm format...
متن کاملChemical Corneal Burning due to an Elective Otoplasty in a Boxer Puppy
Case Description- A 3-month-old female intact Boxer dog was presented to the Veterinary Hospital of Shahid Bahonar University of Kerman with a complaint epiphora, photophobia and corneal opacity of both eyes. Clinical Findings- Ophthalmic examination revealed mild blepharospasm and mucoid discharge of both eyes, with severe bilateral chemosis and c...
متن کاملRabbit corneal allograft survival following topical administration of cyclosporin A.
Cyclosporin A (CS-A), selectively inhibited cellular immunity, delayed the skin graft-induced rejection of corneal allografts in rabbits when administered subconjunctivally in the dose of 3 mg/kg/day or in the form of 5% water-soluble drops five times daily for 28 days. The subconjunctival application of CS-A was irritating, whereas the topical instillation of the water-soluble preparation was ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 9 شماره
صفحات -
تاریخ انتشار 2015